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Most anal cancers seem to be linked to infection with the human papillomavirus (hpv). While hpv infection seems to be important in the development of anal cancer, the vast majority of people with hpv infections do not get anal cancer. A great deal of research is now being done to learn how hpv might cause anal cancer. Anal cancer is an uncommon malignancy that starts in the anus-- the opening at the end of the rectum. The american society of clinical oncology estimates that 8,300 cases of anal cancer will be. Anal cancer is a rare form of cancer that affects the tissues of the anus. We explain what you need to know about its causes and how its diagnosed. Anal cancer is a relatively rare cancer and more common in females than in males. Your risk of developing anal cancer depends on many things, including age and lifestyle factors.

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